Cell Lines and Cell Cultures
Genscript Corporation CHO-K1/GLP1R/G15 Stable Cell
Recombinant CHO-K1 cells stably overexpress human glucagon-like peptide-1 receptor (GLP1R) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/IP1/G15 Stable Cell Li
IP1 receptor is a receptor for prostaglandin I2 or prostacyclin When binding with a prostacyclin molecule the receptor changes conformation and activates Gs Prostaglandin I2 the major product of cyclooxygenase in macrovascular endothelium mediates a potent vasodilation and inhibition of platelet aggregation by binding to this receptor
Genscript Corporation CHO-K1/DP1/G15 Stable Cell Li
DP1 is a G sub s /sub -coupled GPCR expressed in the colon eye platelets eosinophils that bind to PGD2 and PGE2 DP1 can inhibit platelet aggregation and also inhibit leukotriene B4 and superoxide anion (O2-) release from human neutrophils It can relax smooth muscle and regulate eosinophil apoptosis DP receptor knockout OVA-challenged mice exhibit reduced Th2 cytokine levels and lymphocyte accumulation in the lung In addition they failed to produce asthmatic responses
Genscript Corporation CHO-K1/PTH1/G15 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human parathyroid hormone 1 receptor (PTH1) on the surface and contain high levels of G protein G s and G q to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/cyno PD-1 Stable Cell L
Recombinant CHO-K1 cells stably overexpress cynomolgus programmed cell death protein 1 (PD-1) on the surface The surface expression of PD-1 is validated by FACS analysis
Genscript Corporation CHO-K1/MCH2 Stable Cell Line
Coupled exclusively Gq MCH2 is a receptor for melanin-concentrating hormone Other than regulating skin color two subtypes (MCHR1 and MCHR2) are involved in energy homeostasis and social behaviors In contrast to MCHR1 that is conserved among all mammals functional MCHR2 is only expressed in carnivores and primates but not in rodents
Genscript Corporation HEK293/AT1 Stable Cell Line
Recombinant HEK293 cells stably overexpress human angiotensin II receptor type 1 (AT1) on the surface and contain high levels of G protein G q to couple with the receptor in downstream signaling pathways
Genscript Corporation CHO-K1/B7-H2 Stable Cell Line
Ligand for the T-cell-specific cell surface receptor ICOS acts as a costimulatory signal for T-cell proliferation and cytokine secretion It also induces B-cell proliferation and differentiation into plasma cells It could also play an important role in mediating local tissue responses to inflammatory conditions as well as modulating the secondary immune response by co-stimulating memory T-cell function
Genscript Corporation CHO-K1/Mouse CD47 Stable Cell
This gene encodes a membrane protein which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin and it may play a role in membrane transport and signal transduction This gene has broad tissue distribution and is reduced in expression on Rh erythrocytes Alternatively spliced transcript variants have been found for this gene
Bioworld SCC Buffer for Resolve Gels (1X), 40 PK(s)
1X SCC Buffer for Resolve GelsBuffer System: Pre-weighed powder mix in pouches (packs)1 pouch(pack) = 500 mL
STEMCELL Technologies Human Peripheral Blood Leukopak, Fresh, undefined: 9 x 10^8 cells minimum
Obtain large numbers of single-donor mononuclear cells (PBMCs) from normal peripheral blood and reduce the time and reagents required for your downstream cell isolation. Enjoy personalized service, custom products, flexible delivery times, and multiple size options. Leukopaks are highly concentrated, low-volume apheresis collections from normal donors, with Institutional Review Board (IRB)-approved consent forms and protocols. Each full-sized leukopak is produced from ~2 - 3x blood volumes using the Spectra Optia Apheresis System (unless otherwise requested), with ACDA as the anticoagulant. High-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Contact techsupport@stemcell.com for more information, including donor selection or information (BMI category, smoking status, ethnicity, etc.). Donors are recallable and are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories.
STEMCELL Technologies Human Peripheral Blood B Cells, Frozen, Size: 2 x 10^7 cells
Human primary B cells derived from peripheral blood (PB) are isolated from mononuclear cells (MNCs) using the negative immunomagnetic selection technique. Cells are untouched and ready for downstream applications. PB was collected using acid-citrate-dextrose solution A (ACDA) as the anticoagulant.Cells were obtained using Institutional Review Board (IRB)-approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.
STEMCELL Technologies Human Bone Marrow Mononuclear Cells, Frozen, Size: 5 x 10^7 cells
Primary bone marrow mononuclear cells (a.k.a. BM MNCs or BMNCs) are a heterogeneous population that includes hematopoietic lineage cells such as lymphocytes, monocytes, stem cells, and progenitor cells as well as mesenchymal stromal cells. Mononuclear cells are isolated from human adult bone marrow using density gradient separation. Heparin is added to the bone marrow upon collection as an anticoagulant.Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.